preprint
Structured and Target-Specific Development of Cortico-Cortical Connectivity in the Mouse Visual Cortex
BiologyMedicine
Preprint
Computational Peptide Drug Design & Neuroscience
Research in computational peptide drug design and developmental neuroscience using machine learning, evolutionary and stochastic optimization, and statistical and graph-based methods research at UC Santa Cruz and UC Davis.
Recent Publications
Recent peer-reviewed publications from ongoing research collaborations.
preprint
MOAST: Mechanism of Action Similarity Tool
Preprint
8refs
preprint
Massively parallel, single-molecule assessment of synthetic fidelity and drug-like properties in a DNA-encoded library
Preprint
journal article
BPS2025 - Computational design of NaV1.8 sodium channel inhibitors as novel non-addictive treatments for pain management
Biophysical Journal
1recent
journal article
Structural modeling of ion channels using AlphaFold2, RoseTTAFold2, and ESMFold
Channels
19citations
45refs
journal article
Computational design of binders targeting the VSDIV from NaV1.7 sodium channel
Biophysical Journal
Labs
Lokey Lab
Transformer models for molecular property prediction, optimization pipelines for peptide library design, and analysis of high-throughput DNA-encoded library data at UC Santa Cruz.
Kim Lab
Intrinsic signal imaging macroscope development, viral axon tracing quantification, and information-theoretic analysis of cortical connectivity at UC Santa Cruz.
Yarov-Yarovoy Labs
Ion channel structural modeling and computational protein design using AlphaFold2, RoseTTAFold2, ProteinMPNN, and RFDiffusion at UC Davis.